Areas in the Peak District could see snow Friday and Saturday.
According to the current Met Office forecast, snow is expected to start falling in Buxton from 6 p.m. Heavy snow is also expected in the city between midnight and noon. 06.00 Saturday.
The Met Office has also issued a yellow “beware” warning of winds in Derbyshire between midnight and 6pm on Saturday as storm Arwen sweeps in.
Dan Suri, chief meteorologist for the Met Office, said: “Storm Arwen is associated with a deep low pressure system that will mainly affect the northeast from Friday, but which will also bring wider impacts to the UK with high winds, rain and some snow, the high ground .
“Storm Arwen’s impacts are mainly associated with strong winds as the storm sinks south and will largely bring gusts up to 65 mph in coastal areas, albeit slightly stronger in the northeast, with more than 75 mph possible in exposed locations.”
Storm Arwen carries the risk of travel disruption, power outages and potential damage.
RAC crash spokesman Simon Williams said: “The calm weather that large parts of the country are experiencing will end abruptly with the arrival of storm Arwen and will lead to some really challenging driving conditions.
“Strong winds can seriously affect the handling of the vehicle, so drivers must make sure that strong gusts of wind do not surprise them.
“It is important to adjust your driving in windy conditions by slowing down, being very careful when passing high-sided vehicles on exposed motorway sections, as you may be pushed off course and keep a firm grip on the steering wheel.
Riders must also remember to provide extra space for cyclists and motorcyclists when overtaking.
“In extreme windy conditions, bridges can also be closed and trees can fall, so it’s important to allow extra time for travel.
“With weather forecasts predicting strong winds along with colder conditions, drivers should take this opportunity to prepare their vehicles for winter by checking oil and coolant levels.”